Interesting to hear you're going for the change. I thought about going over to Dvorak a while ago, and spent a while reading up on it and considering whether I should learn it.
At the end of the day though, I felt that the difficulties with learning the format far outweighed the potential benefits, so I didn't pursue it any further and quickly forgot about it. It's definitely a nice concept in theory, but in practical terms, as much as I tried, I found it hard to build a case for Dvorak.
Learning it takes a lot of time and effort, and the fact is that the vast, vast majority of keyboards out there used QWERTY. So, anyone who would want to use my computer simply wouldn't be able to, and I consider that a serious downside rather than an amusing quirk, particularly in any professional setting. Also, my skills would not be transferrable if I was going to use another computer, which - especially in this age of ubiquitous computing - reduces the potential benefits a whole lot.
Not only this, but keyboard shortcuts and commands for various programs, and especially games, would be totally screwed up. I'd have to spend time relearning or reconfiguring every program and game I use, which would make me wonder whether the inconvenience and time lost would outweigh the comfort and time gained in typing more quickly.
That said, an even bigger issue for me was the fact that the benefits of Dvorak aren't even proven to be true, as far as I'm aware. Even if there are benefits, they would need to be pretty significant for me to consider it worthwhile.
I don't mean to sound totally negative! I thought Dvorak was quite interesting back in the day and thought I would share what I found. I'm all for people who want to learn Dvorak, I think it sets apart people who are serious about improving their skills at the computer. It'll definitely be interesting to hear how it goes.